652-215 Genes and Genomes

Not available to students enrolled in the BBiomedSc.

Biology 650-141 and 650-142; or biology 650-131 and 650-132 (prior to 2004: 600-141 and 600-142; or biology 600-131 and 600-132).

Upon completion of this subject, students should have:

• an understanding of the molecular basis of gene structure, expression and regulation in prokaryotes and eukaryotes;

• an understanding of DNA replication, recombination and mutagenesis;

• an appreciation of the organisation of genomes in a variety of organisms and the nature of molecular evolution; and

• the skills to solve problems and analyse data using a genetic approach.

The subject provides an introduction to the molecular basis of gene structure and expression in prokaryotes and eukaryotes; the processes of DNA replication, mutation and recombination; the molecular tools of gene isolation and analysis; and molecular evolution.

A written class test held mid-semester (10%); two online tests during the semester (15% in total); a 2-hour written examination in the examination period (75%)

• RJ Brooker, Genetics, Analysis and Principles. 2nd Ed. McGraw-Hill.