610-221 Organic & Bio-organic Chemistry

Credit cannot be gained for this subject and 610-220.

One of chemistry 610-141, 610-121 or 610-051 plus one of 610-142, 610-122 or 610-052. Concurrent enrolment in 610-225 is strongly recommended.

Upon completion, students should have developed an appreciation of the importance of rational, critical and independent thought in the molecular sciences and in their understanding of the chemistry of carbon compounds. Students should have an understanding of the stereochemistry of carbon compounds; the synthesis and some reactions of simple polyfunctional organic compounds, the concept of aromaticity, and the basic types of heterocyclic molecules.

The subject covers molecular architecture and its relationship to chemical and biological change; the principles of organic synthesis: C-C bond formation; the fundamentals of aromatic and heterocyclic chemistry, alkaloids, b-lactams and nucleic acid bases; and amino acids, peptides, proteins and carbohydrates.

This subject will provide the student with the opportunity to establish and develop the following generic skills: problem-solving and critical thinking skills, the ability to use conceptual models to rationalise observations, and an understanding of the changing knowledge base.

A 1-hour multiple-choice examination held during the semester (10%); a 3-hour written examination in the examination period (90%).

• J McMurry, Organic Chemistry. 5th edn, Brooks/Cole, 2000.