536-311 Molecular/Cellular Basis of Physiology

This subject is recommended for BSc students taking a physiology major or BBiomedSci students undertaking a specialisation in molecular and cell biology, integrated systems biology or reproductive and developmental biology.

The subject matter taught in this subject is supported by the experimental investigations presented in 536-304 Advanced Experimental Physiology. It is a recommended companion subject.

At least one of Physiology 536-301, 536-303, 536-308.

The subject will provide a detailed understanding of how molecular and cellular mechanisms control the functional interactions of whole body systems, the integration and coordinated control of physiological systems, homeostasis and adaptations to change. Students will explore the most recent advances in select areas of physiology. Students select among a number of areas of study that reflect the dynamic nature of physiology and research focuses of the department. These include ion and channels and disease; the specialised role of calcium in cell control; genesis and treatment of muscle and injury/disease; gastrointestinal physiology and computational biology; signalling in neuronal cells; perinatal physiology; and stress proteins and skeletal muscle function.

Students develop theoretical background in part using graduate skills in planning, communication, qualitative and quantitative critical analysis in using molecular, biological, biochemical and physiological approaches to investigate physiological processes. Students will be introduced to new technologies that enable the understanding of selected areas of study to be advanced. The assignment is designed to extend teamwork experiences and the ability to read critically and to evaluate and to communicate physiological information. Several of the units offered will be supported with a small group practical investigation in 536-304 Advanced Experimental Physiology.

Two equally weighted 1-hour written examinations, one mid-semester and one late-semester (total 65%); a group poster assignment and presentation due during semester (25%); an individual assignment of not more than 500 words due during semester (10%).