526-304 Principles of Immunology

At least 37.5 points of theory and 12.5 points of practical 200-level subjects from microbiology and immunology, biochemistry, pathology, physiology, anatomy, cell biology or genetics.

BBiomedSc students: 521-213 and 536-250.

By the completion of the course the students should understand and be able to describe:

• the development, function and regulation of cells of the immune system;

• the relationship between structure and function of antibodies;

• the molecular and cellular basis of T cell recognition;

• the molecular and cellular basis of innate immune responses;

• the basis of immune mechanisms underlying immunity to infection and autoimmune disease, hypersensitivity reactions, immunodeficiency diseases and transplant and tumour rejection.

The subject will include coverage of the development, function and regulation of cells of the immune system; immunoglobulins; cytokines; immunological mechanisms operating in immunity to infectious disease; autoimmunity; hypersensitivity; and transplantation and tumour immunology.

A 1-hour written examination held mid-semester (20%); a 3-hour written examination in the examination period (80%).

• A K Abbas and A H Lichtman., Cellular and Molecular Immunology. 5th updated edn, 2005.