521-225 Integrated Biomedical Science

This subject is only available to Bachelor of Biomedical Engineering students

650-131 and 650-132; or 600-131 and 600-132 prior to 2004

This multidisciplinary subject blends biochemistry, molecular and cell biology, tissue biology and physiology, to develop knowledge of the relationship between the structure and function of the major classes of biomolecules, higher ordered structures and cells, as well as the contribution these molecules make to cellular, tissue and whole systems biology. The biochemistry component (36 lectures) covers structure and function of proteins, biological membranes and nucleic acids; and an introduction to recombinant DNA technology, including genome analysis, proteomics and bioinformatics. The cell biology stream (24 lectures) includes the histology and ultrastructure of cells and basic tissue types, epithelium, muscle, nerve, haemopoietic and connective tissues; and the organisation of the major organs and the structure and function of cellular organelles, cytoskeletal structures and the extracellular matrix. The introductory physiology stream (12 lectures) will concentrate on mammalian (especially human) physiology: homeostasis, the relationship between organs and organ systems, cell physiology, excitable cells and electrolyte transport. Practical work will develop basic experimental, data analysis and interpretation skills in biochemistry, physiology and cell and tissue biology techniques. In addition to the specific skills gained, students will think critically and organise knowledge from diverse resources, expand from theoretical principles to practical explanations and acquire abilities in collaborative work.

Two 2-hour end-of-semester examinations on the theory and practical work (70%); laboratory practical work (15%); short (1500-word) written assignment (10%); multiple-choice tests (5%).