521-212 Biochemistry & Molecular Biology Part B

Not available to students enrolled in the BBiomedSc.

Biochemistry 521-211.

Gene expression and metabolism provide cells with the proteins and macromolecules that are essential to carry out their life processes. In this course, metabolic processes will be seen as the outcome of gene expression and regulation, by factors within and external to cells. While we investigate these processes, we achieve an understanding of contemporary work in genomics, proteomics and metabolomics.

The content includes expression, transcription and translation of genes to yield functional proteins; regulation of gene expression; function and regulation of pathways for the catabolic and anabolic metabolism of carbohydrates, lipids and nitrogen-containing compounds in mammalian cells; bioenergetics and mitochondrial function; photosynthesis and carbon fixation. An introduction to the field of signal transduction explores the actions of hormones and their intracellular signalling pathways, critical to health and disease.

The subject is appropriate for all with interests in fundamental research, biotechnology and bioinformatics. This core subject continues from 521-211 as a foundation for a career in the life sciences and is also a frequent choice for double degree students.

In addition to the specific skills gained through study of biochemistry and molecular biology, students should develop the following generic skills:

• the ability to think critically and organise knowledge, from consideration of the lecture material;

• the ability to learn to adopt new ideas, from participation in the lecture program; and

• the ability to plan effective work schedules and grow more confident in the synthesis of knowledge.

Ongoing computer-based assessment during the semester (10%); a 40-minute multiple choice examination held mid-semester (10%); a 3-hour written examination in the examination period (80%)