411-391 Bionanoengineering

411-203 Fluid Mechanics, 431-202 Engineering Analysis B or equivalent, 610-211 Light, Matter and Chemical Change

Nanotechnology and bionanotechnology, history and definition, fine particle fluids, coloidal dispersions and emulsions. The role of surfaces in processing and materials manufacture. Coagulation, electrokinetics, nano-particle dispersion and stability criterion. Inter-particle forces and parameters that influence flow and gelation properties. The role of molecular additives in controlling inter-particle forces and stability. Nano-particle characterisation using light scattering. Solution properties of polymers, macromolecules, self assembly surfactants, lipids, proteins and polysaccharides. The role of self assembly in the formation of structured nano and biomaterials. Cell assembly and molecular components. Nano-particle formation through precipitation. Surface layer structure, functionionalisation and biocompatibility of nano-particles for pharmaceutical, drug delivery biossay, biosensor and immunology applications. Safety and ethical issues in bionanotechnology.

The subject will enhance the following generic skills:

• capacity for independent thought

• the ability to analyse and solve open-ended problems

• the ability to comprehend complex concepts and communicate lucidly this understanding

• awareness of advanced technologies in the discipline

• ability to work in a team (practical work component)

One written 3-hour end-of-semester examination (80%); one assignment of up to 4000 words (not including appendices and diagrams and tables) due in the second half of the semester (20%).