652-302 Molecular Genetics

Genetics 652-214 and 652-215.

BBiomedSc students: Genetics 652-214, 521-213 and 536-250.

Upon completion of the subject students should have:

• developed a general appreciation of the molecular basis of genetic processes in both prokaryotes and eukaryotes;

• understood all of the basic techniques of recombinant DNA analysis and genomics and be able to appreciate how these methods are applied to specific biological problems;

• obtained an understanding of how knowledge in molecular genetics is obtained and presented by the study of primary research papers and review articles; and

• acquired the basic concepts and knowledge to enable them to do more advanced courses in a wide range of areas of cellular and molecular biology.

The topics covered will be prokaryote gene structure, action and regulation; genomic and recombinant DNA methodology; eukaryotic gene structure, action and regulation; genetic manipulation of microorganisms, plants and animals and genetic engineering; genome structure, prokaryotic and eukaryotic mobile DNA elements; and the genetic control of the cell cycle.

A 3-hour end-of-semester written examination; mid-semester tests or up to three problems/assignments of not more than 1000 words each.