652-215 Genes and Genomes

Biology 600-141 and 600-142 or biology 600-131 and 600-132.

Upon completion of this subject students should have:

• an understanding of the molecular basis of gene structure, expression and regulation in prokaryotes and eukaryotes;

• an understanding of DNA replication, recombination and mutagenesis;

• an appreciation of the organisation of genomes in a variety of organisms and the nature of molecular evolution; and

• the skills to solve problems and analyse data using a genetic approach.

The subject provides an introduction to the molecular basis of gene structure and expression in prokaryotes and eukaryotes; the processes of DNA replication, mutation and recombination; the molecular tools of gene isolation and analysis; and molecular evolution.

One 3-hour written examination at the end of the semester and up to four short-answer tests during semester.

• A J F Griffiths, J H Miller, W M Gelbart, R C Lewontin, D T Suzuki, An Introduction to Genetic Analysis. 7th ed.