610-221 Organic & Bio-organic Chemistry

One of chemistry 610-141, 610-161 or 610-051 AND one of 610-142, 610-162 or 610-052. Concurrent enrolment in 610-225 is strongly recommended.

Upon completion of 610-221 students should have an understanding of the stereochemistry of carbon compounds; the synthesis and some reactions of simple polyfunctional compounds; the concept of aromaticity; the basic types of heterocyclic compounds; the main classes of biologically significant organic compounds; and some of the important aspects of pharmaceutical organic chemistry.

Students should also appreciate the importance of rational, critical and independent thought in chemical science and in the understanding of organic chemistry.

The subject covers the topics molecular architecture and its relationship to chemical and biological change (nine lectures); principles of organic synthesis; C-C bond formation (nine lectures); fundamentals of aromatics and heterocyclic chemistry (six lectures); alkaloids, ß-lactams and nucleic acid bases (three lectures); amino acid, peptides, proteins and carbohydrates (nine lectures)

One 3-hour written examination at the end of semester. Assignments and tests may constitute up to 10% of the final assessment.

• J McMurry, Organic Chemistry. 5th ed., Brooks/Cole, 2000.