536-250 Integrated Biomedical Science II

521-213 Integrated Biomedical Science I

The overall aim will be to build on the knowledge developed in Integrated Biomedical Science I and to extend coverage to include the intermediary metabolism, organ and whole systems physiology and tissue biology, genes and gene expression and the major regulatory systems. The biochemistry stream (24 lectures) will cover metabolism, bioenergetics, waste elimination, regulation of metabolism including the molecular basis of cell signalling, molecular mechanisms and regulation of gene replication, expression and protein synthesis. Biochemistry will also combine with physiology to cover integrated whole body responses to metabolic and physiological stress and nutrition. The physiology stream (48 lectures) will concentrate on the transduction of neurotransmitter, hormone and other messages; control systems common to many organs, the autonomic nervous system and the endocrine system. Coverage of specific organ systems will include renal, respiratory and cardiovascular systems, digestive and excretory, reproductive, locomotor, neurophysiology (taught with relevant histology and structure in conjunction with anatomy and cell biology). The practical work will be designed to develop and extend experimental, data analysis and interpretation skills in biochemistry and physiology techniques.

Two 2-hour end-of-semester examination on theory and practical work (70%); practical work (15%); two short written assignments (500 words each) and computer-based tests (15%).