526-311 Medical Microbiology: Pathogens

Microbiology 526-201 and 526-221 and one or more of the following: biochemistry 521-211 and 521-212, or genetics 652-214 and 652-215.

BBiomedSc students: microbiology 526-201 or 526-205; 521-213 and 536-250.

Upon completion of this course, students should be able to:

• understand the basic principles of virology, bacteriology and parasitology in terms of the structure, molecular taxonomy, replication and gene expression of infectious agents;

• apply information obtained from microbial genomics to the investigation of infectious diseases;

• show how etiological relationships are established and how molecular techniques are being used in the diagnosis of infections; and

• understand the rational basis of anti-microbial therapy using their knowledge of microbial structure and replication, and how new anti-microbials might be developed.

A 3-hour end-of-semester written examination (80%); a 1-hour mid-semester written examination (20%)

• C Mims et al, Medical Microbiology. 2nd ed., Mosby, 1998.
  or
  Schaechter et al, Mechanisms of Microbial Disease. 3rd ed., Williams and Wilkins, 1998.

• A A Salyers and D D Whitt, Bacterial Pathogenesis - A Molecular Approach. ASM Press, 1994.
• D O White and F Fenner, Medical Virology. 4th ed., 1994.