521-322 Protein Biochemistry and Proteomics

Note

Credit Points

HECS Band

Coordinator

Prerequisites

Biochemistry and molecular biology 521-211, 521-212 and either 521-220 or 521-221; or 521-024; or 521-213 plus physiology 536-250.

Semester

Contact

Subject Description

By the end of the subject the student should have developed skills in the experimental approaches and techniques used in advanced investigations of protein structure, and in the critical evaluation of the experimental data derived from such methods; applied these skills to a number of specific protein-based experimental systems; and developed skills in computer applications, including experimental simulations and graphics applications relevant to protein chemistry and proteomics. The content will include modern biochemistry methods and database analysis for characterising protein structure, function and expression; experiments that emphasise aspects of protein unfolding, determination and analysis of ligand binding data; and the use of computers in the analysis and prediction of protein structure. Students will be required to present written accounts of experimental results and use computers for analysing results and molecular graphics applications. Experimental work will be organised into elective streams, one of which will involve an opportunity to undertake relevant project work within one of the Department's research laboratories (quota will apply).

Assessment

Three components will be assessed: 1. laboratory skills and practical management of the experimental program; 2. written research report(s); 3. a written assignment of up to 2000 words or a 2-hour written examination (to be advised at the commencement of the subject).