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 531-301 Cellular Basis of Disease

Note

This subject may be taken as the only Pathology subject or as part of a year-long Pathology course. To enrol in 531-302 and 531-303 or 531-304, a pass grade must be achieved in 531-301

Credit Points

25

Coordinator

Dr M M Ayers

Prerequisites

Basic Principles of Pathology 531-201; Biochemistry and Molecular Biology 521-211+521-212 and 521-221+521-222.

Highly recommended: Anatomy and Cell Biology 516-201.

Semester

1 (view timetable)

Contact

36 lectures (three per week) and a total of 54 hours practical (6 x 6h laboratory-based practicals; 6 x 3h written practicals)

Subject Description

Students completing this subject will:

  • extend and deepen studies of the principles of Pathology begun in 531-201, through the scientific study of the causes, mechanisms of development and the possible outcomes of disease;

  • understand the cellular and molecular basis of defence and repair processes commonly used by the body when a malfunction of a tissue/organ occurs;

  • appreciate the spectrum and limitations of the possible biological mechanisms of response to injury, and be able to relate these mechanisms to those which have been established as the basis of normal cell/molecular biology;

  • gain a deeper theoretical and practical understanding of the way in which questions about disease processes are formulated and investigation of these questions is carried out using sophisticated laboratory-based techniques.

Practicals will comprise hands-on laboratory exercises and written exercises based on provided experimental data.

The topics to be studied are cell injury; repair, regeneration, fibrosis; infectious disease; immunopathology; haemo-dynamic disorders; vascular disease; growth disorders including neoplasia.

Assessment

A 3-hour end-of-semester written examination, 2 multiple choice examinations to be held during the semester.

Prescribed Texts
  • Cotran R S, Robbins Pathologic Basis of Disease. Latest Edition, Saunders.
    or
    Rubin E and Farber J L, Pathology. Latest Edition, Lippincott.
Search : Index : Faculty of Science : Pathology
Prev 531-202 Basic Principles of Pathology -Optometry
Next 531-302 Molecular/Genetic Basis of Disease-Lect
 
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