652-215 Genes and Genomes

Note

Credit cannot be granted for both 652-215 and either 652-201 or 652-205.

Credit Points

Coordinator

Prerequisites

Principles of Genetics 652-214 or 652-204. (Exemption may be given by Departmental Head.)

Semester

Contact

Subject Description

Upon completion of this subject students should have:

• an understanding of the molecular basis of gene structure, expression and regulation in prokaryotes and eukaryotes;
• an understanding of DNA replication, recombination and mutagenesis;
• an appreciation of the organization and structure of genomes in a variety of organisms and the nature of molecular evolution;
• the skills to solve problems and analyse data using a genetic approach.

The subject provides an introduction to the molecular basis of gene structure and expression in prokaryotes and eukaryotes. The processes of DNA replication, mutation and recombination. The molecular tools of gene isolation and analysis. Molecular evolution.

Assessment

One 3-hour written examination at the end of the semester; one mid-semester short answer test.

Prescribed Texts

• Griffiths A J F, Miller J H, Gelbart W M, Lewontin R C, Suzuki D T, An Introduction to Genetic Analysis. 6th ed..