521-322 Techniques in Protein Biochemistry

Credit Points

Coordinator

Prerequisites

Biochemistry and Molecular Biology 521-222 or (pre 1997) 521-202, 521-301 and 521-321.

Semester

Contact

Subject Description

By the end of the subject the student should have: developed skills in the experimental approaches and techniques used in the investigation of protein structure, and in the critical evaluation of the experimental data derived from such methods, applied these skills to a number of experimental systems which illustrate the effectiveness of specific advanced techniques and developed skills in computer applications, including experimental simulations and graphics applications relevant to protein chemistry. The content will include: experiments that emphasise investigations of protein unfolding, determination and analysis of ligand binding data and the use of computers in the analysis and prediction of protein structure. Students will be required to present written and oral accounts of experimental results and use computers for analysing results and molecular graphics applications. Experimental work will be organised into elective streams, one of which will involve an opportunity to undertake relevant project work within one of the Department's research laboratories (quota will apply).

Assessment

This subject will be assessed on the basis of performance in the laboratory (15%), tutorial and written reports and poster presentation (45%) and a 2 hour end-of-semester written examination (40%).