250-203 Veterinary Pathology

Note:

Coordinator:

Timetable:

Contact:

Objectives:

Students completing this subject should:

• be familiar with, and able accurately to apply, the terminology of pathology;

• understand the principles and possess the essential information regarding the major causes of disease and the responses of cells and tissues to injury;

• understand the molecular basis of pathological processes;

• be able to observe precisely and to identify, describe and interpret the macroscopic and microscopic appearances of tissues and cells altered by disease processes;

• be familiar with the sources and able to use contemporary literature relating to the principles of pathology; and

• be aware of the capabilities and limitations of the methods of experimental pathology and of special examinations such as biopsy, radiology and clinical pathology.

Content:

Causes of disease. Processing of animal tissues. Special stains and procedures. Disturbances of growth. Cell injury and adaptation. Cell and tissue death (necrosis). Body defence mechanisms. Biology of leucocytes. Inflammation. Repair and regeneration. Circulatory disturbances. Immune-mediated disease, mechanisms of tissue injury in hypersensitivity reactions. Autoimmunity, amyloidosis, immunodeficiency, animal analogues of acquired immunodeficiency disease, immunotolerance. Genetic abnormalities and embryological malformations. Inherited and non-inherited congenital abnormalities of animals. Host-parasite interactions. Abnormal accumulations. Nutritional pathology. Toxicologic pathology. Neoplasia. Introduction to systemic pathology.

Assessment:

Prescribed Texts:

• Cheville, N F, Introduction to Veterinary Pathology, (3rd ed.), 1988, Saunders.
• Slauson, D O and Cooper, B J, Mechanisms of Disease, (2nd ed.), 1990, Williams and Wilkins.
• Duncan, J R and Prasse, K W, Veterinary Laboratory Medicine, (2nd ed.), 1995, Iowa State University Press.
• Moulton, J. E., Tumours in Domestic Animals, 3rd ed., 1991, University of California Press.