Handbook 1996 : Faculty of Science (Volume 4 page 224)
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Note: This subject must be taken in conjunction with 534-307. Experiments involving the use of animals are an essential part of this subject; exemption is not possible.
Credit points: 12.0
Coordinator: Dr D D Leaver
Pre/Corequisite: Prerequisites: Pharmacology 534-301; 534-302 is highly recommended. Corequisite: Pharmacology 534-307
Contact: 78 hours practical (one six-hour session a week)
Timetable: Second semester
Objectives:
By the end of the program in Toxicology (practical) the student should:
- have developed skills to perform toxicological investigations with small laboratory animals (rodents) according to animal ethics guidelines; to prepare and characterise microsomal tissue fractions for studies on xenobiotic metabolism and toxicity; to utilise a variety of in vitro systems to illustrate the mechanisms of toxicity of drugs and xenobiotics; to examine the nature of potential environmental toxicants in water; to utilise a computer database for the retrieval of toxicological data.
- appreciate the nature of animal and in vitro toxicity tests used in the pre-clinical testing of drugs.
Content:
The action of commonly-used drugs such as paracetamol, and common environmental pollutants such as lead, examined on cell and tissue models.
Assessment:
Continuous assessment throughout the subject; a 1-hour computer based practical examination.
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Handbook 1996 : Faculty of Science (Volume 4 page 224)
Status: Official 1996 Date created: Oct 9 1995 Last modified: Oct 9 1995 Authorised by: Academic Registrar Email enquiries: Course_Information@registrar.unimelb.edu.au
Maintained by: Dept. of Pharmacology, Faculty of Medicine, Dentistry and Health Sciences.
Copyright © University of Melbourne 1995,1996.