Handbook 1996 : Faculty of Science (Volume 4 page 221)
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531-304 Molecular Pathology A

Note: Credit is not available for both Pathology 531-304 and 531-305.

Credit points: 15.0

Coordinator: Dr J R Underwood. Deputy Coordinator: Dr M M Ayers.

Prerequisite: General Pathology 531-301 or 531-302; Biochemistry and Molecular Biology 521-201, 521-202*

• Students should note that although these prerequisites are considered essential, interested applicants without these requirements should apply and will be considered on their merits.

Recommended: Pathology 531-303; Biochemistry and Molecular Biology 521-301 or Microbiology 526-304

Contact: 39 lectures (three a week)

Timetable: Second semester only

Objectives:

Students completing this subject should:

• understand the molecular basis of a variety of disease processes which have as a common theme a disturbance of function at the level of the cell membrane;
• integrate this knowledge with the general principles of Cellular Pathology provided in 531-301 and 531-303.

Content:

Molecular pathological processes and cell surface molecules of disease; immune mechanisms of tissue damage; immune deficiency diseases; auto-immune diseases; immunohematology; immunogenetic principles of HLA and human blood groups; immunoglobulin gene structure and expression; aspects of transplantation biology. Cell surface molecules in diseases of the nervous system, renal system, hepatobiliary system and in neoplastic processes. Diseases associated with growth factors and their receptors.

Assessment:

A 2-hour end-of-semester written examination.

Prescribed texts:

• As for 531-301 and Brostoff et. al. Clinical Immunology. Gower Medical Publishers 1991 or Abbas et. al. Cellular and Molecular Immunology Saunders 1991

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Handbook 1996 : Faculty of Science (Volume 4 page 221)

Status:          Official 1996
Date created:    Oct  9 1995
Last modified:   Oct  9 1995
Authorised by:   Academic Registrar
Email enquiries: Course_Information@registrar.unimelb.edu.au

Copyright © University of Melbourne 1995,1996.