Handbook 1996 : Faculty of Science (Volume 4 page 171)
Biochemistry subject : Next:521-305 | Prev:521-303 | Search | Help
521-304 "Molecular Basis of Hormone Action and Neutro-Transmission" appears differently in several places - choose the one you want:
1. Biochemistry, Faculty of Science (v4, p171) : Next:521-305 | Prev:521-303
Credit points: 10.0
Coordinator: Dr B G Livett
Prerequisite: Biochemistry and Molecular Biology 521-201 and 521-202, or Biological Chemistry 521-024. In special circumstances, the Head of the Department may permit students who have not taken Biochemistry 521-202 to enrol in this subject.
Contact: 26 lectures (two a week)
Timetable: Second semester
Objectives:
By the end of the program the student should have acquired:
- A detailed understanding of the current concepts of the molecular basis for endocrinology and neuroendocrinology;
- An appreciation of the similarities in the mechanism of action of hormones, polypeptide growth factors and neuro-transmitters, particularly in relation to signal transduction processes;
- A theoretical background to the major biochemical techniques used to investigate the molecular basis for hormone and neurotransmitter action;
- An overview of the fundamental areas of metabolism subject to hormonal and neurotransmitter action.
Content:
The controls exerted by cellular regulatory processes: metabolic targets for regulation, rate limiting steps in metabolism. The endocrine system and target tissues for individual hormones. Biosynthesis, storage and secretion of hormones and neurotransmitters. Receptors for hormones, growth factors and neurotransmitters. Mechanisms in signal transduction with particular emphasis on second messenger and protein phosphorylation-dependent pathways. Hormonal regulation of gene expression. Metabolic consequences of regulation by hormones and neurotransmitters in specialised tissues. Polypeptide growth factors: structure, function, tissue distinction and mechanism of action. Nerve growth and differentiation factors. Molecular recognition events of importance during the development of the nervous system. Tissue specialisation within the nervous system and the different roles of neuropeptides and other neurotransmitters. The neurochemistry of myelin and multiple sclerosis, Parkinson's, Huntington's and Alzheimer's diseases.
Assessment:
A 2-hour end-of-semester written examination
Prescribed texts:
1. Biochemistry, Faculty of Science (v4, p171) : Next:521-305 | Prev:521-303
2. Agriculture, Faculty of Agric, For & Hort (v4, p19) : Next:521-305 | Prev:521-303
Year 4 Agriculture.
Credit points: 8
Coordinator: Dr B G Livett.
Prerequisite: 521-024 Biological Chemistry
Contact: 26 hours of lectures.
Timetable: Second semester
See additional details under the Biochemistry subject above.
* Note that CONTACT, POINTS, PREREQUISITES, TITLE differs from the maintainer's version above. A log of variations is available.
2. Agriculture, Faculty of Agric, For & Hort (v4, p19) : Next:521-305 | Prev:521-303
Status: Official 1996 Date created: Oct 9 1995 Last modified: Oct 9 1995 Authorised by: Academic Registrar Email enquiries: Course_Information@registrar.unimelb.edu.au
Maintained by: Dept. of Biochemistry & Molecul.Biology, Faculty of Medicine, Dentistry and Health Sciences.
Copyright © University of Melbourne 1995,1996.