Handbook 1996 : Faculty of Medicine, Dentistry and Health Sciences (Volume 4 page 136)
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Year 3 Medicine.
Contact: Three lectures and a 90-minutes museum session a week; a 3- hour practical class a week (including a 1-hour tutorial) from early in the first semester to the middle of the second semester; occasional 1-hour integration seminars (All year).
Objectives:
On completion of this subject, student should:Comprehend and be able to describe: the characteristics and behaviour of microorganisms and their relationship to clinical manifestations of infection; the principles of the modes of spread and pathogenesis of infection; the epidemiology and control of infectious disease; the principles of antimicrobial chemotherapy; the characteristics, components and mechanisms of immune responses to infection and the possible abnormalities of responses in infection and other disease states.
Have developed: basic skills in working in an aseptic environment; skills in applying and interpreting the results of, the relevant diagnostic tests to specific case studies; observational skills in identifying the appearance and behaviour of medically significant microorganisms; the ability to collect transport and make preliminary investigations of clinical specimens.
Appreciate: the need for rational use and interpretation of microbiological investigations and for rational judgements about the use of antibiotics; the means of preventing and controlling infectious diseases at the level of both the community and the individual; how the skills learned in microbiology will be integrated and utilised in subsequent clinical practice.
Content:
Characteristics of pathogenic microorganisms: Bacteria, viruses, rickettsiae, fungi, protozoa, helminths. Pathogenesis of infection: Mechanisms of disease production. Laboratory diagnosis of infectious disease: Respiratory, alimentary, C. N. S. , urinary, sexually-transmitted, systemic and congenital infections. Collection of specimens, laboratory investigations, interpretation of reports. Epidemiology and control of infectious disease: Routes of transmission of infection. Sanitation. Vaccines, immunisation. Sterilisation and disinfection. Hospital-acquired infections. Antimicrobial chemotherapy: Mode of action of antibiotics and chemotherapeutic agents. Mechanisms of resistance. Antibiotic sensitivity testing. Clinical applications. Immunology: Ontogeny, organisation and functional development of the immune system. Characterisation and effector functions of subpopulations. MHC restriction. Tolerance and immune suppression. Immunoglobulins, cytokines, complement. Hypersensitivity. Antimicrobial immunity. Autoimmunity and immunodeficiency. MHC antigens - graft rejection and disease associations. Practical Work: Based principally on case studies which present microbiological and immunological material in conjunction with clinical history. Most practical sessions include a tutorial for which students read prescribed articles and prepare answers to pre-set questions. Lecture and practical material is integrated with museum demonstrations, self-instructional question-answer sheets and seminars dealing with key topics.
Assessment:
A 1-hour written examination at the end of the first semester (15 per cent). A 3-hour written examination (55 per cent) and a 2-hour practical examination (30 per cent) at the end of the second semester.
Prescribed texts:
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Handbook 1996 : Faculty of Medicine, Dentistry and Health Sciences (Volume 4 page 136)
Status: Official 1996 Date created: Oct 9 1995 Last modified: Oct 9 1995 Authorised by: Academic Registrar Email enquiries: Course_Information@registrar.unimelb.edu.au
Maintained by: Dept. of Microbiology, Faculty of Medicine, Dentistry and Health Sciences.
Copyright © University of Melbourne 1995,1996.